Abstract:

Proliferative diabetic retinopathy is a major cause of blindness. Recently a large number of basic and clinical studies have shown that the treatments of intravitreal anti-vascular endothelial grow factor(VEGF) injection combined with panretinal photocoagulation or vitrectomy can achieve a good effect and reduce surgical complications. But using timing of anti-VEGF is an issue in clinic. A preoperative intravitreal injection can make the operation more easy, while intraoperative injection reduces the  operation frequency. Surgeons should choose appropriate injection timing according to the patient situation to greatly benefit patients.(Int Rev Ophthalmol,2015,39:333.336)